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Whitening Efficacy of 3% Carbamide Peroxide Gel Activated by Lactoperoxidase
Mehdi Khemiss1,2,3, Ines Kallel3,4,5, Hela Zouaghi1,3,4
1Department of Dental Medicine, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Objective:
The aim of this clinical study was to evaluate the effectiveness of a whitening toothpaste containing 3% carbamide peroxide and lactoperoxidase. Materials and methods. Participants were instructed to brush their teeth using an enzymatic-activated dentifrice following a particular procedure for three weeks. Color was recorded before and after treatment using a VITA Easyshade spectrophotometer. Differences in L (tooth color lightness), a (displacement along the red-green axis), and b (displacement along the yellow-blue axis) were measured before and after treatment using the paired t and the Wilcoxon signed-rank tests. Color changes (Δ ) were calculated using the obtained measurements.
Results:
Thirty-four volunteers were included. Δ was 4.03. For the set of 348 teeth, a greater tendency towards green (lower a ) and blue (lower b ) was observed (p < 0.05). There were no significant differences in lightness after treatment. Mandibular central incisors showed a greater tendency towards green (lower a ) and blue (lower b ). Bleaching effectiveness was observed in both the upper and lower central incisors and in the lateral mandibular incisors.
Conclusion:
Based on these results, it may be concluded that brushing with an enzymatic-activated dentifrice is effective for whitening teeth.

