Related Experiment Video
Updated: Nov 2, 2025

Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
Published on: August 11, 2023
Concomitant acute limb ischemia and multiple acute ischemic strokes complicating COVID-19: a case report
Falmata Laouan Brem1, Taha Abu-Al-Tayef2, Hammam Rasras1
1Department of Cardiology, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy of Oujda, Oujda, Morocco.
Insights
Coronavirus disease 2019 (COVID-19) can cause severe arterial thrombotic events, including limb ischemia and strokes. This case highlights the critical need for anticoagulation in COVID-19 patients to prevent such vascular complications.
Area of Science:
- Cardiology
- Infectious Diseases
- Vascular Medicine
Background:
- The COVID-19 pandemic has seen a rise in cardiovascular complications, particularly thrombotic events in critically ill patients.
- While venous thromboembolism is common in SARS-CoV-2 infection, arterial thromboembolism is less frequently reported.
Observation:
- A case of COVID-19 is presented with concurrent acute right limb ischemia and multiple acute ischemic strokes.
- This presentation signifies a severe manifestation of the hypercoagulable state associated with SARS-CoV-2 infection.
Findings:
- The patient experienced both limb ischemia and cerebral ischemia, indicating widespread arterial thrombotic complications.
- This case underscores the potential for severe arterial events in COVID-19 patients, even beyond venous thromboembolism.
Implications:
- The findings emphasize the importance of recognizing and managing the hypercoagulable state in COVID-19.
- Proactive anticoagulation therapy is crucial for preventing severe arterial thrombotic events and improving outcomes in SARS-CoV-2 infected individuals.
Abstract:
Since the spread of the coronavirus disease 2019 (COVID-19) pandemic, cardiovascular complications are interestingly increasing, particularly thrombotic events, especially in those requiring intensive care. Venous thromboembolism is well known to occur in patients infected by the SARS-CoV-2, but only a few arterial thromboembolism cases have been previously reported. Herein, we report the case of a COVID-19 complicated by a concomitant acute right limb ischemia and multiple acute ischemic strokes. This rare case emphasizes the hypercoagulable state described in COVID-19 patients and the need for anticoagulation therapy to prevent these severe complications.
Related Concept Videos
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Acute Coronary Syndrome IV: Interprofessional Care
Acute Coronary Syndrome III: Diagnostic Studies
Acute Coronary Syndrome V: Nursing Management
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...

