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Updated: Nov 2, 2025

Point-of-Care Ultrasound: A Review of Ultrasound Parameters for Predicting Difficult Airways
Published on: April 7, 2023
Useful Ultrasonographic Parameters to Predict Difficult Laryngoscopy and Difficult Tracheal Intubation-A Systematic
Sara H Gomes1,2, Ana M Simões1,2, Andreia M Nunes1,2
1School of Medicine, Life and Health Sciences Research Institute (ICVS), University of Minho, Braga, Portugal.
Ultrasonography can predict difficult airways. The hyomental distance in a neutral position is the most reliable pre-operative airway ultrasound assessment parameter for predicting difficult laryngoscopy and tracheal intubation.
Area of Science:
- Anesthesiology and critical care medicine
- Medical imaging
- Otolaryngology
Background:
- Unexpected difficult airway management poses significant risks, including morbidity and mortality, during elective procedures.
- Ultrasonography shows promise for perioperative airway assessment, but specific sonographic predictors for difficult laryngoscopy and tracheal intubation remain unclear.
- Routine application of ultrasonography for airway assessment requires identification of reliable predictive parameters.
Approach:
- A systematic review and meta-analysis was conducted to identify ultrasonographic predictors of difficult airways.
- Literature search included PubMed, Web of Science, and Embase, focusing on human primary studies predicting difficult laryngoscopy or tracheal intubation using ultrasonography.
- Data from 19 articles (4,570 patients) for the systematic review and 12 articles (1,141 patients) for the meta-analysis were analyzed using PRISMA methodology.
Key Points:
- Twenty-six sonographic parameters were evaluated for their predictive value.
- Significant parameters included skin-to-hyoid bone distance, skin-to-epiglottis distance, skin-to-anterior commissure of vocal cords distance, pre-epiglottis space to epiglottis-vocal cord midpoint distance, hyomental distance in neutral and extended positions, and the ratio of hyomental distance in neutral to extended positions.
- Hyomental distance in the neutral position emerged as the most reliable parameter.
Conclusions:
- Hyomental distance in the neutral position is the most dependable ultrasonographic parameter for pre-operative airway assessment.
- Limitations include small sample sizes, study heterogeneity, and the lack of a standardized ultrasonographic evaluation method.
- Further research with standardized methods and larger sample sizes is warranted to confirm these findings.
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