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Related Experiment Video

Updated: Nov 2, 2025

Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies
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Integrative Medicine: Herbal Supplements.

Matthew K Hawks1, Paul F Crawford1, David A Moss2

  • 1F. Edward Hébert School of Medicine at the Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814.

FP Essentials
|June 15, 2021
PubMed
Summary
This summary is machine-generated.

Herbal supplements are popular plant-based health products, but their safety and effectiveness vary. Physicians should discuss herbal supplement use with patients due to potential risks and drug interactions.

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Area of Science:

  • Integrative Medicine
  • Pharmacology
  • Public Health

Background:

  • Herbal supplements, derived from plants, have a long history of use for health preservation.
  • Their popularity has surged in the U.S. over recent decades.
  • Physician-patient communication regarding herbal supplement use is often inadequate.

Purpose of the Study:

  • To highlight the increasing use of herbal supplements.
  • To underscore the importance of physician inquiry into patient supplement use.
  • To inform about the variable safety and efficacy of herbal products.

Main Methods:

  • Review of current trends in herbal supplement popularity.
  • Analysis of physician and patient reporting behaviors.
  • Examination of regulatory oversight by the Food and Drug Administration (FDA).

Main Results:

  • Many physicians do not inquire about herbal supplement use, and a third of patients do not disclose their use.
  • While some herbal supplements are low risk, others pose significant adverse effects, such as drug interactions (e.g., St. John's wort).
  • Clinical data supporting the effectiveness of herbal supplements varies widely by condition.

Conclusions:

  • Physician awareness and patient disclosure of herbal supplement use are crucial for patient safety.
  • The Food and Drug Administration (FDA) primarily handles postmarketing safety concerns.
  • Adverse events related to herbal supplements should be reported to the FDA via MedWatch.