Related Experiment Video
Updated: Nov 2, 2025

08:05
Bioluminescence and Near-infrared Imaging of Optic Neuritis and Brain Inflammation in the EAE Model of Multiple Sclerosis in Mice
Published on: March 1, 2017
9.4K
Neuroimaging findings in rheumatologic disorders
Sedat Giray Kandemirli1, Girish Bathla1
1University of Iowa Hospital and Clinics, Department of Radiology, USA.
Journal of the Neurological Sciences
|June 15, 2021
Summary
Rheumatological diseases can affect the nervous system, causing neurological symptoms. Magnetic resonance imaging (MRI) is crucial for diagnosing central nervous system (CNS) involvement in these patients.
Area of Science:
- Neurology
- Rheumatology
- Radiology
Background:
- Rheumatological diseases can manifest with neurological symptoms affecting the central nervous system (CNS) and peripheral nervous system.
- These neurological symptoms may stem from the primary rheumatological condition or as a side effect of immunosuppressive therapies.
- Prompt diagnosis and treatment are vital to avert severe neurological complications.
Purpose of the Study:
- To review the neuroimaging manifestations of various rheumatic diseases.
- To emphasize the specific findings on Magnetic Resonance Imaging (MRI) for CNS involvement in rheumatological conditions.
Main Methods:
- Literature review of neuroimaging findings in rheumatological diseases.
- Focus on Magnetic Resonance Imaging (MRI) characteristics.
Main Results:
- MRI is the preferred imaging modality for suspected CNS involvement due to its detailed soft tissue visualization.
- The review highlights characteristic MRI findings associated with different rheumatic diseases affecting the CNS.
Conclusions:
- Neurological manifestations are a significant concern in patients with rheumatological diseases.
- MRI plays a pivotal role in the early diagnosis and management of CNS involvement in rheumatological disorders.
Related Concept Videos
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
158
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
158
Genome-wide Association Studies-GWAS
14.8K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
14.8K

