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[Pancreatitis following kidney transplantation]
Schweizerische Medizinische Wochenschrift
|February 4, 1978
Summary
Pancreatitis developed in 14 of 249 kidney transplant recipients, with steroid medication being a key factor. This complication led to a 7% mortality rate among transplant recipients, highlighting its significance.
Area of Science:
- Nephrology
- Gastroenterology
- Transplantation Medicine
Context:
- Post-transplant complications following cadaver renal allografts.
- Long-term follow-up of organ transplant recipients.
Purpose:
- To investigate the incidence and outcomes of pancreatitis in renal allograft recipients.
- To identify contributing factors and mortality associated with post-transplant pancreatitis.
Summary:
- A 2.5 to 12.5-year follow-up of 249 renal allograft recipients identified 14 cases of pancreatitis.
- Acute pancreatitis occurred within 4 months in 9 patients, with 5 deaths from hemorrhagic-necrotizing pancreatitis.
- Overall mortality from pancreatitis in this cohort was 7 out of 14 cases (7% of all transplant fatalities), with steroid medication identified as a primary contributing factor.
Impact:
- Highlights pancreatitis as a significant, potentially fatal complication after renal transplantation.
- Underscores the critical role of immunosuppressive therapy, particularly steroids, in post-transplant pancreatitis.
- Informs clinical monitoring and management strategies for renal transplant recipients.