Live births after Asherman syndrome treatment
Miriam M F Hanstede1, Eva van der Meij1, Sebastiaan Veersema2
1Spaarne Gasthuis, Department of Obstetrics and Gynecology, Asherman Expertise Center, Haarlem, The Netherlands.
Objective:
To study the reproductive outcomes after surgical management of women with Asherman syndrome (AS).
Design:
Cohort study.
Setting:
International referral hospital for women with AS.
Patient(S):
A total of 500 women who were diagnosed with and treated for AS between January 2003 and December 2016 and followed for a minimum of 2 years.
Intervention(S):
Hysteroscopic adhesiolysis using conventional instruments with concomitant fluoroscopy as a guidance method.
Main Outcome Measure(S):
Live birth rate.
Result(S):
Of the 500 women included in the cohort, 569 pregnancies were achieved within 3 years after surgery. The miscarriage rate was 33.0%, and the live birth rate was 67.4%. Age, the causal procedure, and at least one miscarriage after adhesiolysis strongly predicted the outcome of a live birth.
Conclusion(S):
The overall take-home newborn rate was 67.4% after adhesiolysis in women with AS. Women with AS who are relatively young, with a first-trimester procedure preceding AS, and with low grades of adhesions and no miscarriage after adhesiolysis have the best chance of a newborn delivery.
More Related Videos
09:39Generation of Induced Pluripotent Stem Cells from Turner Syndrome 45XO Fetal Cells for Downstream Modelling of Neurological Deficits Associated with the Syndrome
Published on: December 4, 2021
11:53Laparoscopic Oocyte Retrieval and Cryopreservation during Vaginoplasty for Treatment of Mayer-Rokitansky-Kuster-Hauser Syndrome
Published on: May 10, 2022
Related Concept Videos
02:57Meiosis vs. Mitosis
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
01:07Teratogenicity