Related Experiment Video

Updated: Nov 2, 2025

Simultaneous Electrocardiography Recording and Invasive Blood Pressure Measurement in Rats
07:35

Simultaneous Electrocardiography Recording and Invasive Blood Pressure Measurement in Rats

Published on: January 31, 2019

15.8K

Electrocardiographic differences in patients with true and pseudo-resistant hypertension

Mehmet Eyuboglu1, Baris Acikel2

  • 1Department of Cardiology, Gaziosmanpasa University School of Medicine, Tokat, Turkey. mhmtybgl@gmail.com.

Journal of Human Hypertension
|June 16, 2021
PubMed

Insights

Fragmented QRS (fQRS) and frontal plane QRS-T angle are novel electrocardiogram (ECG) markers that can predict true resistant hypertension in patients with uncontrolled blood pressure. These ECG parameters may help identify patients at higher risk for cardiovascular events.

Area of Science:

  • Cardiology
  • Medical Diagnostics

Background:

  • Cardiovascular disease is a leading cause of mortality in hypertensive patients.
  • True resistant hypertension significantly increases the risk of premature cardiovascular events.
  • Electrocardiography (ECG) is crucial for monitoring hypertensive heart disease, but specific ECG parameters for resistant hypertension require further investigation.

Purpose of the Study:

  • To investigate the predictive value of fragmented QRS (fQRS) and frontal plane QRS-T angle for true resistant hypertension.
  • To assess if these novel ECG parameters can identify patients with uncontrolled blood pressure who have true resistant hypertension.

Main Methods:

  • A prospective study involving 406 hypertensive patients with resistant hypertension.
  • Patients were categorized into 'true resistant' and 'pseudo-resistant' hypertension groups.
  • Comparison of ECG parameters, including fQRS and frontal plane QRS-T angle, between the two groups.

Main Results:

  • True resistant hypertension was identified in 18% of patients.
  • fQRS and frontal plane QRS-T angle were significantly higher in the true resistant hypertension group.
  • ROC analysis indicated that a frontal plane QRS-T angle > 90.75° predicted true resistant hypertension with 96% sensitivity.
  • fQRS in anterior leads and frontal plane QRS-T angle were independent predictors of true resistant hypertension.

Conclusions:

  • Fragmented QRS and frontal plane QRS-T angle are potential predictors of true resistant hypertension.
  • These ECG parameters may aid in identifying patients with uncontrolled blood pressure who have true resistant hypertension.
  • Further research can explore the clinical utility of these ECG markers in managing resistant hypertension.

More Related Videos

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice09:56

Implantation of Combined Telemetric ECG and Blood Pressure Transmitters to Determine Spontaneous Baroreflex Sensitivity in Conscious Mice

Published on: February 14, 2021

5.5K
Patient Directed Recording of a Bipolar Three-Lead Electrocardiogram using a Smartwatch with ECG Function05:03

Patient Directed Recording of a Bipolar Three-Lead Electrocardiogram using a Smartwatch with ECG Function

Published on: December 11, 2019

8.9K

Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
164
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
2.0K
Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
259
Special considerations while measuring blood pressure01:28

Special considerations while measuring blood pressure

When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
902
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
3.4K
Electrocardiogram01:29

Electrocardiogram

An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
4.3K