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Diffuse Gallbladder Adenomyomatosis in a Child.
Hong Duc Pham1, Minh Xuan Ngo2, Thu Ha Dang1
1Radiology, Hanoi Medical University, Hanoi, VNM.
Cureus
|June 16, 2021
Summary
Diffuse gallbladder adenomyomatosis (GA) is an uncommon benign condition. This case report details a rare presentation in a young female, emphasizing diagnostic challenges and the need for differential diagnosis from malignancy.
Area of Science:
- Gastroenterology
- Pathology
- Radiology
Background:
- Adenomyomatosis of the gallbladder (GA) is a benign proliferative condition characterized by gallbladder wall thickening and Rokitansky-Aschoff sinuses (RAS).
- The diffuse form of GA is an uncommon subtype, typically seen in middle-aged individuals.
Observation:
- A 17-year-old female presented with chronic right hypochondriac pain.
- Imaging studies revealed marked diffuse gallbladder wall thickening.
- Gross examination showed a diffusely enlarged gallbladder.
Findings:
- Histopathology confirmed diffuse gallbladder adenomyomatosis with muscular and epithelial hyperplasia.
- Epithelial invaginations formed characteristic Rokitansky-Aschoff sinuses (RAS).
- The condition was associated with chronic inflammation.
Implications:
- This case underscores the rarity of diffuse GA in adolescents.
- Diagnostic challenges include differentiating from gallbladder malignancies, particularly without cholesterol crystal "comet tail" signs.
- Highlights the importance of histopathological confirmation for accurate diagnosis.
