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Related Concept Videos

Pulmonary Embolism I: Introduction01:29

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Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
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Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
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Barrett Esophagus-II: Clinical Manifestations and Management01:21

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Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
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Endoscopic Studies II: Thoracocentesis01:26

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Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
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Acute Respiratory Failure-III01:30

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Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
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Fatal systemic (paradoxical) air embolism diagnosed by postmortem funduscopy.

Lucy M Bradley1, Anna G McDonald2, Patrick E Lantz2

  • 1Department of Pathology, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA.

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|June 16, 2021
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Retinal air emboli (RAE) are a rare sign of systemic air embolism. This case report documents RAE in an infant, aiding in diagnosing fatal air embolism through postmortem examination.

Keywords:
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Area of Science:

  • Forensic Pathology
  • Ophthalmology
  • Pediatric Medicine

Background:

  • Systemic air embolism is frequently underdiagnosed.
  • Retinal air emboli (RAE) are a rare but distinctive sign of systemic air embolism.
  • Published literature lacks photographic documentation of RAE, particularly in pediatric cases.

Observation:

  • An infant presented unresponsive and later died despite resuscitation.
  • Postmortem funduscopy revealed diagnostic RAE.
  • Radiography and autopsy confirmed systemic paradoxical air embolism from inflicted blunt force trauma.

Findings:

  • This case report provides the first photographic evidence of RAE in an infant.
  • The findings illustrate classic RAE associated with fatal systemic air embolism.
  • RAE were detected during postmortem funduscopy.

Implications:

  • The detection of RAE can assist pathologists in diagnosing systemic air embolism.
  • This case highlights the importance of funduscopy in postmortem examinations.
  • Recognizing RAE can improve the diagnosis of air embolism in critical care and forensic settings.