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Kikuchi-Fujimoto Disease With Unusual Cutaneous Findings
Gregory A Gates1, Yunfeng Li2, Clara Magyar2
1Division of Dermatopathology, UCLA Medical Center, Department of Pathology & Lab Medicine, Los Angeles, CA.
Abstract:
We present a case of the rare Kikuchi-Fujimoto disease (KFD) in a 14-year-old patient admitted to UCLA Medical Center with fever, weight loss, and pancytopenia. Physical examination revealed tender subcutaneous nodules and cervical lymphadenopathy. A lymph node biopsy showed findings consistent with KFD. The skin biopsy showed mild superficial dermal edema with neutrophil-predominant inflammation. In addition, rare atypical monocytoid cells were seen. This histologic finding of a Sweet-like morphology has not been reported previously in the literature in association with KFD. The differential diagnosis included Sweet syndrome arising in association with KFD, underlying connective tissue, and an infectious etiology.
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