Burden of osteoporosis in Vietnam: An analysis of population risk
Duy K Hoang1,2, Minh C Doan1,2,3, Linh D Mai1,2,3
1Bone and Muscle Research Group, Ton Duc Thang University, Ho Chi Minh, Vietnam.
Insights
Nearly half of older women and over a third of older men in Vietnam are eligible for osteoporosis treatment. This study highlights the need for targeted interventions to reduce fracture risk in this population.
Area of Science:
- Gerontology
- Bone Health
- Public Health
Background:
- Osteoporosis is a significant public health concern, increasing fracture risk in aging populations.
- Effective osteoporosis management is crucial for preventing debilitating fractures and maintaining quality of life in older adults.
Purpose of the Study:
- To determine the proportion of men and women aged 50 and above in Vietnam classified as high-risk for fracture.
- To assess eligibility for anti-fracture treatment based on established criteria.
Main Methods:
- A population-based study in Ho Chi Minh City, Vietnam, included 1421 women and 652 men aged 50+.
- Bone mineral density (BMD) measured via DXA; osteoporosis diagnosed using T-scores ≤ -2.50.
- 10-year fracture risks calculated using FRAX (Thai version); treatment eligibility based on US National Osteoporosis Foundation (NOF) criteria.
Main Results:
- Prevalence of osteoporosis was 27% in women and 13% in men.
- 49% of women and 35% of men met NOF criteria for osteoporosis treatment eligibility.
- While major fracture risk was low, hip fracture risk eligibility was notable.
Conclusions:
- A substantial proportion of older adults in Vietnam, particularly women, require osteoporosis treatment.
- These findings support the development of localized osteoporosis management guidelines in Vietnam.
- Early identification and treatment are key to mitigating fracture risk in the Vietnamese elderly.
Purpose:
To estimate the proportion of men and women aged 50 years and older who would be classified as "high risk" for fracture and eligible for anti-fracture treatment.
Methods:
The study involved 1421 women and 652 men aged 50 years and older, who were recruited from the general population in Ho Chi Minh City, Vietnam. Fracture history was ascertained from each individual. Bone mineral density (BMD) was measured at the lumbar spine and femoral neck by DXA (Hologic Horizon). The diagnosis of osteoporosis was based on the T-scores ≤ -2.50 derived from either femoral neck or lumbar spine BMD. The 10-year risks of major fractureand hip fracture were estimated from FRAX version for Thai population. The criteria for recommended treatment were based on the US National Osteoporosis Foundation (NOF).
Results:
The average age of women and men was ~60 yr (SD 7.8). Approximately 11% (n = 152) of women and 14% (n = 92) of men had a prior fracture. The prevalence of osteoporosis was 27% (n = 381; 95% CI, 25 to 29%) in women and 13% (n = 87; 95% CI, 11 to 16%) in men. Only 1% (n = 11) of women and 0.1% (n = 1) of men had 10-year risk of major fracture ≥ 20%. However, 23% (n = 327) of women and 9.5% (n = 62) of men had 10-year risk of hip fracture ≥ 3%. Using the NOF recommended criteria, 49% (n = 702; 95% CI, 47 to 52%) of women and 35% (n = 228; 95% CI, 31 to 39%) of men would be eligible for therapy.
Conclusion:
Almost half of women and just over one-third of men aged 50 years and older in Vietnam meet the NOF criteria for osteoporosis treatment. This finding can help develop guidelines for osteoporosis treatment in Vietnam.
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