Related Experiment Video

Updated: Nov 2, 2025

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
07:44

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

6.1K

Upper Gastrointestinal Endoscopy with biopsy in paediatric feeding disorders

Robyn Robinson1, Nicholas Placone2, Mitchell Katz1,3

  • 1CHOC Children's, Orange, CA, USA.

Acta Paediatrica (Oslo, Norway : 1992)
|June 16, 2021
PubMed

Insights

Children with persistent feeding problems show higher rates of eosinophilic esophagitis (EoE) compared to controls. Upper endoscopy may be warranted for unresolved pediatric feeding disorders.

Area of Science:

  • Pediatric Gastroenterology
  • Digestive Endoscopy
  • Esophageal Disorders

Background:

  • Persistent feeding problems in children are a common concern.
  • Upper gastrointestinal (GI) pathology can contribute to feeding difficulties.
  • The role of endoscopy in evaluating pediatric feeding disorders requires further investigation.

Purpose of the Study:

  • To compare upper GI pathology found during endoscopy in children with feeding problems versus controls.
  • To determine the prevalence of esophagitis, including eosinophilic esophagitis (EoE), in these groups.

Main Methods:

  • Esophagogastroduodenoscopy (EGD) biopsy results were analyzed.
  • Two age-matched cohorts were studied: 86 children in a feeding clinic and 86 controls referred for other reasons.
  • Biopsy findings were statistically compared between the feeding and control groups.

Main Results:

  • Abnormal endoscopy biopsies were found in 57% of the feeding cohort and 53% of controls.
  • Microscopic esophagitis was present in 30% of the feeding group and 26% of controls (p=0.98).
  • Eosinophilic esophagitis (EoE) was diagnosed in 15.1% of the feeding group and 8% of controls (p=0.15), a significant increase.

Conclusions:

  • While abnormal biopsies and microscopic esophagitis rates were similar, EoE incidence was notably higher in children with feeding disorders.
  • The tripling of EoE incidence in the feeding group compared to previous reports warrants attention.
  • Persistent pediatric feeding disorders may necessitate upper endoscopy evaluation.
Abstract

Keywords:
endoscopyeosinophilic oesophagitismicroscopic oesophagitispaediatric feeding disorders

More Related Videos

Author Spotlight: Advancing Biopsy Techniques with Transesophageal Ultrasound04:35

Author Spotlight: Advancing Biopsy Techniques with Transesophageal Ultrasound

Published on: November 21, 2023

768

Related Concept Videos

Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
478
Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
1.3K
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
388
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
273
Upper GI Series: Barium Swallow01:24

Upper GI Series: Barium Swallow

The Barium Swallow Study, or a Barium Esophagogram, is a diagnostic imaging method used to visualize the upper gastrointestinal (GI) tract, including the esophagus, stomach, and small intestine. It employs barium sulfate, a radiopaque contrast material, to provide clear images of the upper digestive system, helping to identify abnormalities, diseases, or structural issues.
Purpose and Procedure
Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...
1.1K
Endoscopic Procedures III: Video Capsule Endoscopy01:28

Endoscopic Procedures III: Video Capsule Endoscopy

Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
406