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[Cough: physiology and pathophysiology].

P Leuenberger1

  • 1Département de médecine interne, Centre hospitalier universitaire vaudois, Lausanne.

Schweizerische Medizinische Wochenschrift
|June 25, 1988
PubMed
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Coughing is a vital reflex protecting lungs from irritants and clearing airways. However, various conditions can impair cough effectiveness, potentially leading to adverse effects.

Area of Science:

  • Pulmonology
  • Physiology

Background:

  • Cough is a complex physiological reflex crucial for lung protection and airway clearance.
  • Effective coughing relies on high expiratory airflow and dynamic airway compression.

Purpose of the Study:

  • To elucidate the physiological mechanisms of an effective cough.
  • To identify pathological conditions compromising cough efficacy.

Main Methods:

  • Review of physiological principles governing cough reflex.
  • Analysis of factors affecting expiratory flow and airway dynamics.

Main Results:

  • Effective cough requires high airflow velocities, dependent on expiratory flow and airway caliber reduction.
  • Pathological conditions like reflex pathway dysfunction, reduced expiratory flows, and altered airway geometry impair cough efficacy.

Related Experiment Videos

  • Impaired cough can result from issues with mucociliary clearance and changes in bronchial secretions.
  • Conclusions:

    • Cough's protective function is essential but can be compromised by numerous pathological factors.
    • Understanding these factors is critical for managing conditions associated with ineffective or harmful coughs.