Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Viral Mutations00:36

Viral Mutations

36.4K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
36.4K
Point and Frameshift Mutations01:30

Point and Frameshift Mutations

336
Point mutations are genetic alterations involving the change of a single nucleotide base pair in DNA. Depending on how the alteration affects protein synthesis, they can lead to various consequences.Point mutations fall into the following types:Silent mutations occur when a nucleotide change does not alter the amino acid sequence due to the redundancy of the genetic code. For instance, changing ACC to ACA still encodes threonine, leaving the protein function unaffected. This occurs because...
336
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

7.6K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
7.6K
Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

17.1K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
17.1K
Mutations01:35

Mutations

41.6K
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
41.6K
Mutations01:39

Mutations

87.3K
Overview
87.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy and safety evaluation of artificial intelligence-identified antimicrobial peptides targeting avian pathogenic Escherichia coli in broiler chickens.

Journal of animal science and biotechnology·2026
Same author

AIEdit: Alignment-free genome assembly polisher trained on spaced seed match patterns.

PLoS computational biology·2026
Same author

ntStat: k-mer characterization using occurrence statistics in raw sequencing data.

PLoS computational biology·2026
Same author

AMPSeek: A Workflow for Predicting Antimicrobial Peptide Activity, Three-Dimensional Structure, and Toxicity.

Current protocols·2026
Same author

A comprehensive tandem repeat catalog of the human genome.

Nature communications·2026
Same author

ntSynt: multi-genome synteny detection using minimizer graph mappings.

BMC biology·2025
Same journal

Sentiment Analysis of Acceptance TVET Online Courses on the Skill Academy App from Google Play: Leveraging Text Mining with Comparison Machine Learning Model.

F1000Research·2026
Same journal

Emotional intelligence: An important skill to learn now more than ever.

F1000Research·2026
Same journal

East Mediterranean Lineage of <i>Brucella melitensis</i> in Human Isolates and Milk Samples in Oman Using MLVA-14.

F1000Research·2026
Same journal

Application of K-Means Clustering for Job Applicant Analysis in Construction Firms Using R.

F1000Research·2026
Same journal

The influence of self-esteem and emotional intelligence on addiction to social networks in Peruvian university students.

F1000Research·2026
Same journal

A Bibliometric Analysis of Music's Role in Promoting Well-Being in Health Science Research.

F1000Research·2026
See all related articles

Related Experiment Video

Updated: Nov 2, 2025

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells
10:34

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells

Published on: December 9, 2022

4.7K

Interactive SARS-CoV-2 mutation timemaps.

René L Warren1, Inanc Birol1

  • 1Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, V5Z 4S6, Canada.

F1000Research
|June 23, 2021
PubMed
Summary
This summary is machine-generated.

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly mutates. Interactive maps visualize daily nucleotide variations in SARS-CoV-2 genomes across continents, revealing its evolution during the COVID-19 pandemic.

Keywords:
COVID-19GISAIDInteractive SVGMutation time mapsSARS-CoV-2

More Related Videos

Author Spotlight: Advancing Pathogen Diagnostics with Standardized LAMP
05:34

Author Spotlight: Advancing Pathogen Diagnostics with Standardized LAMP

Published on: September 8, 2023

987
Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

1.1K

Related Experiment Videos

Last Updated: Nov 2, 2025

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells
10:34

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells

Published on: December 9, 2022

4.7K
Author Spotlight: Advancing Pathogen Diagnostics with Standardized LAMP
05:34

Author Spotlight: Advancing Pathogen Diagnostics with Standardized LAMP

Published on: September 8, 2023

987
Following the Dynamics of Structural Variants in Experimentally Evolved Populations
04:52

Following the Dynamics of Structural Variants in Experimentally Evolved Populations

Published on: February 3, 2023

1.1K

Area of Science:

  • Virology
  • Genomics
  • Epidemiology

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, has seen the emergence of new viral strains.
  • Understanding the scale and patterns of SARS-CoV-2 mutation is crucial for tracking its evolution.

Purpose of the Study:

  • To visualize and comprehend the geographical and temporal mutation patterns of SARS-CoV-2.
  • To provide a tool for analyzing daily nucleotide variations in viral genomes.

Main Methods:

  • Development of interactive scalable vector graphics (SVG) maps.
  • Comparison of daily nucleotide variations against the initial SARS-CoV-2 genome.
  • Analysis of genomic data from six populated continents.

Main Results:

  • The study presents daily mutation time maps illustrating SARS-CoV-2 evolution.
  • Visualizations highlight the scale and geographical distribution of viral mutations.
  • The ntEdit tool facilitates mutation analysis.

Conclusions:

  • Interactive visualizations effectively demonstrate the rapid evolution of SARS-CoV-2.
  • The provided resources enable tracking of viral mutations in near real-time.
  • Understanding viral evolution aids in managing the COVID-19 pandemic.