Clinical diagnosis of oral erosive and ulcerative diseases in children
Related Experiment Video
Updated: Nov 1, 2025

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
1Stomatology Hospital.
Insights
Pediatric oral mucosal diseases, including erosion and ulceration, are common and painful, impacting children's daily activities. Diagnosis involves clinical examination and may require further tests for accurate identification.
Area of Science:
- Pediatric Dentistry
- Oral Medicine
- Dermatology
Background:
- Oral mucosal diseases are prevalent in children, with erosions and ulcerations comprising approximately 50% of cases.
- These conditions often present acutely, causing significant pain that interferes with speech, eating, and swallowing.
- Some oral mucosal diseases in children are infectious and can lead to outbreaks.
Purpose of the Study:
- To review the research progress on oral mucosal diseases in children.
- To summarize clinical experiences with oral erosive and ulcerative diseases in pediatric patients.
Main Methods:
- Comprehensive medical history and physical examination are crucial for diagnosis.
- Diagnostic tools include biopsy, blood tests, immunofluorescence staining, immunohistochemistry, molecular biology detection, gene diagnosis, and tuberculin testing.
- Therapeutic diagnosis and secondary biopsy may be employed when initial investigations are inconclusive.
Main Results:
- Diagnosis can often be achieved through medical history and clinical manifestations alone.
- A range of diagnostic tests are available for complex or unclear cases.
- Multidisciplinary consultation and investigation of systemic diseases are sometimes necessary.
Conclusions:
- Accurate diagnosis of pediatric oral mucosal diseases relies on a combination of clinical assessment and appropriate investigations.
- Early and precise diagnosis is essential for effective management and to prevent complications.
- Further research and clinical experience are vital for advancing the understanding and treatment of these conditions.
Abstract:
Mucosal disease is one of the most common oral cavity diseases in children, among which mucosal erosion and ulceration account for about 50%. Oral mucosal erosion and ulcer diseases in children are mostly acute with obvious pain, affecting speech, eating and swallowing. Some oral mucosal diseases are caused by infection and would result in epidemic among children. The onset age, sites, lesions size and quantity could vary, and some would have recurrence. The detailed medical history and comprehensive physical examination are necessary, some diseases can be diagnosed according to the medical history and clinical manifestations. If diagnosis can not be made, biopsy, blood test and immunofluorescence staining, immunohistochemistry, molecular biology detection, gene diagnosis, tuberculin test and other tests should be considered, and further investigation of systemic diseases should also be carried out if necessary. In some cases, multidisciplinary consultation should be sought. For those who still have no abnormal findings, therapeutic diagnosis can be tried out or secondary biopsy should be performed. In this article, the research progress of oral mucosal diseases in children is reviewed and our own clinical experiences of oral erosive and ulcerative diseases in children are summarized.
Related Concept Videos
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...

