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Published on: July 5, 2021
Bilateral optic nerve compression secondary to skull hyperostosis from vitamin A deficiency
Sherief Raouf1, Sylvia Kodsi1, Hal Schwartzstein1
1Northwell Health Department of Ophthalmology, Great Neck, New York.
Abstract:
A 15-year-old boy with a history of autism spectrum disorder presented with bilateral progressive blurry vision and nyctalopia. Initial examinations, including optical coherence tomography scans of the macula and optic nerve, were within normal limits. Subsequent examination revealed trace pallor of the right optic nerve. Computed tomography and magnetic resonance imaging of the brain demonstrated diffuse thickening of calvarial bone with bilateral optic nerve compression. Laboratory evaluation was notable for profound vitamin A deficiency. The patient underwent optic nerve decompression and vitamin A supplementation with postoperative improvement in visual acuity of both eyes.
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