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Chronic active hepatitis with cirrhosis in the Doberman pinscher
T S van den Ingh1, J Rothuizen, R Cupery
1Department of Veterinary Pathology, State University Utrecht, Faculty of Veterinary Medicine, The Netherlands.
The Veterinary Quarterly
|April 1, 1988
Abstract:
Chronic active hepatitis with cirrhosis and increased liver copper levels in 8 female (3 spayed) Doberman Pinschers is described. The response to immunosuppressive therapy in two dogs was poor. Laboratory results were not specific for the disease in the Doberman Pinscher and may occur in other liver diseases. The increased copper levels are most probably secondary to hepatocellular cholestasis. Although the pathogenesis is unknown, the disease in the Doberman Pinscher may be regarded as a separate entity.