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Systematic Coronary Risk Evaluation (SCORE): JACC Focus Seminar 4/8.
Ian M Graham1, Emanuele Di Angelantonio2, Frank Visseren3
1Trinity College, Dublin, Ireland.
Journal of the American College of Cardiology
|June 18, 2021
Summary
Clinical risk estimation is unreliable, leading to the development of systems like the European Society of Cardiology
Area of Science:
- Cardiology and Public Health
- Cardiovascular Disease Risk Stratification
Background:
- Clinical estimation of combined cardiovascular risk factors is often unreliable.
- Risk estimation systems are crucial for guiding clinical practice and public health strategies.
Purpose of the Study:
- To review the evolution of the European Society of Cardiology's (ESC) Systematic COronary Risk Evaluation (SCORE) system.
- To outline future directions for cardiovascular risk estimation, including SCORE 2 and personalized lifetime risk assessment.
Main Methods:
- Review of the development and learnings from the ESC's SCORE risk estimation system.
- Description of the ESC's Cardiovascular Risk Collaboration and its research agenda.
Main Results:
- SCORE 2 will provide updated, calibrated risk estimates for total cardiovascular events across European regions.
- Future directions include expressing risk as years of exposure and utilizing genetic data for individualized lifetime risk estimation.
Conclusions:
- Cardiovascular risk estimation is evolving towards more refined and personalized approaches.
- Future systems may incorporate genetic information and lifetime exposure for more accurate risk prediction.
