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Hemadsorption as a Treatment Option for Multisystem Inflammatory Syndrome in Children Associated With COVID-19. A

Juan Carlos Ruiz-Rodríguez1,2, Luis Chiscano-Camón1,2, Clara Palmada1,2

  • 1Intensive Care Department, Vall d'Hebron University Hospital, Barcelona, Spain.

Frontiers in Immunology
|June 18, 2021
PubMed

Insights

Multisystem Inflammatory Syndrome in Children (MIS-C) linked to COVID-19 involves severe inflammation. A hemadsorption device was used to manage the cytokine storm in affected children.

Area of Science:

  • Pediatrics
  • Immunology
  • Infectious Diseases

Background:

  • Multisystem Inflammatory Syndrome in Children (MIS-C) is a serious condition linked to COVID-19.
  • MIS-C presents with hypercytokinemia, causing excessive inflammation.
  • Cytokine storm is a critical aspect of severe MIS-C.

Observation:

  • The study describes the application of a hemadsorption device.
  • This device was utilized as a component of supportive care.
  • The intervention targeted the cytokine storm in pediatric patients.

Findings:

  • Hemadsorption devices can be integrated into the management of MIS-C.
  • This approach addresses the hyperinflammatory state characteristic of the syndrome.
  • The use of hemadsorption offers a potential strategy for supportive treatment.

Implications:

  • This highlights a novel therapeutic option for severe MIS-C cases.
  • Further research may explore the efficacy and outcomes of hemadsorption in pediatric critical care.
  • Managing cytokine storm with devices like hemadsorbers could improve patient prognoses.

Keywords:
SARS-CoV-2cytokine - immunological termshemoadsorptioninflammatory multisystemic syndromemyocardial injury

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