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Updated: Jul 10, 2026

Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
[Reproducibility of the quantitative indices of the global and regional function of the left ventricle when
Abstract:
10 healthy persons were examined by two left ventriculographies--conventional and hemiaxial. The results show good and exceptionally good reproducibility (r = 0.80 up to 0.90) of the quantitative indices for global left ventricular function in all projections with the exception of the end systolic volume index of the left ventricule in the cranial left anterior oblique projection (r = 0.67) and of the ejection fraction in the left oblique projections (r = 0.6 and 0.68). The results of the segmental analysis of the left ventricular wall movements show good reproducibility in the four projections (p greater than 0.1) in spite of the fact that the models used depend on the exact determination of the cardiac apex.

