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Updated: Nov 1, 2025

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Site-specific Incorporation of 2',5'-Linked Nucleic Acids Enhances Therapeutic Profile of Antisense Oligonucleotides

Thazha P Prakash1, Jinghua Yu1, Wen Shen1

  • 1Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, California 92010, United States.

ACS Medicinal Chemistry Letters
|June 18, 2021
PubMed

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