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Cuffless blood pressure estimation based on haemodynamic principles: progress towards mobile healthcare
Takehiro Yamakoshi1,2, Peter Rolfe3,4, Ken-Ichi Yamakoshi5,6,7
1Institute of Liberal Arts and Science, Kanazawa University, Kanazawa, Ishikawa, Japan.
Peerj
|June 18, 2021
Summary
A new smartphone-based method accurately estimates blood pressure (BP) without a cuff, using photoplethysmogram data. This cuffless BP monitoring offers a convenient alternative to traditional methods for mobile healthcare.
Area of Science:
- Biomedical Engineering
- Cardiovascular Technology
- Digital Health
Background:
- Traditional cuff-sphygmomanometry for blood pressure (BP) measurement is inconvenient.
- Existing cuffless BP monitoring methods often lack accuracy.
- Previous smartphone-based methods required extensive calibration models.
Purpose of the Study:
- To develop a novel, highly accurate cuffless blood pressure estimation method.
- To overcome limitations of previous calibration-dependent BP monitoring techniques.
- To leverage smartphone-derived photoplethysmogram data for BP assessment.
Main Methods:
- Utilized modified normalized pulse volume (mNPV) and pulse rate (PR) from smartphone photoplethysmograms.
- Implemented an initial calibration procedure using cuff-based BP, mNPV, and PR.
- Calculated estimated BP (BP_e) using a formula derived from hemodynamic Ohm's law: BP_e = (BP_c0 * PR * mNPV) / (PR_0 * mNPV_0).
Main Results:
- High agreement between cuff-based and estimated BP values observed (correlation coefficients: 0.968 for SBP, 0.934 for MBP, 0.844 for DBP).
- Bland-Altman analyses confirmed good agreement, with mean absolute differences < 5 mmHg.
- Demonstrated good tracking of BP trends over time in individual subjects.
Conclusions:
- Successfully developed a new cuffless BP estimation method.
- The method shows significant potential as a convenient substitute for conventional sphygmomanometers.
- Applicable to smartphones, smartwatches, and finger-based devices for mobile healthcare.
Keywords:
Blood pressureCufflessHaemodynamic principleHealthcareHeart diseaseHypertensionMobile healthModified normalized pulse volumeSmartSmartphoneMore Related Videos
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