Does neonatal manipulation on continuous or alternate days change maternal behavior?

Débora da Silva Bandeira Rêgo1, Jaime Moreira Pires1, Maira Licia Foresti2

  • 1Department of Physiology, Universidade Federal de São Paulo, São Paulo, Brasil.

Maternal separation and neonatal manipulation of pups produce changes in maternal behavior after the dam-pup reunion. Here, we examined whether continuous versus alternating days of neonatal manipulation during the first 8 postnatal days produces differential changes in maternal and non-maternal behaviors in rats. We found that both maternal separation protocols increased anogenital licking after dam-pup reunion, reflecting increased maternal care of pups.