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Screening test for COVID-19 in dental practice: Best options
Sandra López-Verdín1, José R Prieto-Correa2, Nelly Molina-Frechero3
1Health Science University Center, Institute for Dental Research, University of Guadalajara, Jalisco, Mexico, patologiabucal@live.com.mx.
Rapid screening tests like real-time loop-mediated isothermal amplification (RT-LAMP) and real-time recombinase polymerase amplification (RT-RAP) can help dental practices identify patients with potential COVID-19, preventing cross-infection.
Area of Science:
- Infectious Diseases
- Diagnostic Technologies
- Dental Public Health
Background:
- Biological risk management in dental settings traditionally relies on personal protective equipment and surface disinfection.
- The absence of effective antiviral treatments or vaccines for SARS-CoV-2 necessitates improved diagnostic strategies.
Purpose of the Study:
- To review diagnostic tests suitable for screening dental patients for potential COVID-19.
- To identify rapid and reliable screening tools for use in dental practices.
Main Methods:
- Comprehensive literature searches were conducted in Medline, PubMed, and EBM Review databases (2019-2020).
- Exclusion criteria included real-time polymerase chain reaction (RT-PCR) and Western blot assays.
Main Results:
- Real-time loop-mediated isothermal amplification (RT-LAMP) and real-time recombinase polymerase amplification (RT-RAP) emerged as promising screening methodologies.
- These tests can aid in identifying patients potentially carrying SARS-CoV-2 within dental settings.
Conclusions:
- RT-LAMP and RT-RAP offer viable screening options for dental practices to mitigate SARS-CoV-2 transmission.
- Rapid and reliable detection of SARS-CoV-2 is crucial for preventing infections among patients and dental personnel.
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