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Summary
Vesicoureteral reflux (VUR) rarely causes azotemia, but surgery can improve or stabilize kidney function in affected patients. Early surgical intervention is recommended for severe VUR to prevent irreversible renal damage.
Area of Science:
- Nephrology
- Pediatric Urology
Background:
- Vesicoureteral reflux (VUR) is a common condition in children.
- Azotemia, a sign of impaired kidney function, is a rare complication of VUR.
Observation:
- A review of over 600 VUR cases identified only 21 with coexisting azotemia.
- These patients had moderate azotemia, with creatinine levels below 3.5 mg/dL.
Findings:
- Eleven patients underwent successful surgical correction for VUR.
- Nine of these patients showed improvement or stabilization of their renal function post-surgery.
Implications:
- Surgical intervention for VUR may be beneficial in preventing irreversible renal function deterioration.
- Early surgical treatment is advised for severe VUR or cases with evidence of renal parenchymal damage.