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Follicular Dendritic Cell Sarcoma of the Chest
Ilkka K Ilonen1, Andrew J Meltzer2, Sharif Ellozy3
1Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
The Annals of Thoracic Surgery
|June 20, 2021
Summary
Follicular dendritic cell sarcoma, a rare cancer, can present as a mediastinal mass. This case highlights successful surgical treatment of aortic-involved sarcoma using an endovascular stent graft.
Area of Science:
- Oncology
- Surgical Oncology
- Vascular Surgery
Background:
- Follicular dendritic cell sarcoma (FDCS) is a rare, low-grade malignancy originating from follicular dendritic cells within the lymphoid system.
- These tumors are uncommon and can present in various locations, sometimes involving vital structures.
Observation:
- A 57-year-old male patient was incidentally found to have a mediastinal mass with aortic involvement.
- The discovery occurred during an investigation for unrelated indeterminate pulmonary nodules.
Findings:
- The mediastinal mass was diagnosed as follicular dendritic cell sarcoma.
- The patient underwent successful treatment involving surgical resection.
- An endovascular aortic stent graft was utilized to aid in the surgical management of the aortic involvement.
Implications:
- This case demonstrates a successful multimodal approach for managing rare FDCS with complex aortic involvement.
- The use of endovascular techniques in conjunction with surgery offers a viable option for similar challenging cases.
- Highlights the importance of thorough evaluation of incidental findings in the mediastinum.

