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Pulmonary Hemorrhage Revealing Multiple Vascular Malformations in a Child with KCNT1 Developmental Epileptic

Julie Cassibba1, Lauren Bitton1, Cyril Mignot2

  • 1Pediatric Pulmonology Department, Trousseau Hospital, Assistance Publique - Hôpitaux de Paris (AP-HP), Sorbonne Université.

The Journal of Pediatrics
|June 20, 2021
PubMed
Abstract

No abstract available in PubMed .

Keywords:
childdevelopmental and epileptic encephalopathyhemoptysispotassium channelvascular malformation

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Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
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Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
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