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Time in Range in Pregnancy: Is There a Role?
Jennifer A Wyckoff1, Florence M Brown2
1University of Michigan, Ann Arbor, MI.
Summary
Continuous glucose monitoring (CGM) helps manage diabetes in pregnancy. New targets, like time in range (TIR), are vital for improving outcomes for both mother and baby.
Area of Science:
- Endocrinology
- Maternal-Fetal Medicine
- Diabetes Technology
Background:
- Continuous glucose monitoring (CGM) adoption is rising in pregnancy management.
- Improving CGM accuracy and patient preference drive its use.
- Evolving data link CGM metrics, like time in range (TIR), to pregnancy and neonatal outcomes.
Purpose of the Study:
- To explore the relationship between CGM metrics and outcomes in pregnancies with diabetes.
- To highlight the need for pregnancy-specific TIR targets.
- To assess the role of CGM in hybrid closed-loop insulin systems for gestational diabetes.
Main Methods:
- Analysis of CGM data in pregnant individuals with diabetes.
- Evaluation of associations between various CGM metrics and pregnancy/neonatal outcomes.
- Review of current literature on TIR targets and hybrid closed-loop systems in pregnancy.
Main Results:
- Standardized novel targets based on CGM data are emerging.
- Pregnancy-specific TIR parameters are demonstrably lower than for nonpregnant individuals.
- CGM is integral to hybrid closed-loop insulin delivery systems.
Conclusions:
- Further understanding of CGM metrics in diabetic pregnancies is required.
- Optimizing TIR is crucial for successful hybrid closed-loop insulin delivery in pregnancy.
- CGM offers significant potential for advancing diabetes management during pregnancy.
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