Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Viruses with RNA Genomes01:29

Viruses with RNA Genomes

278
RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
278
Viruses of Archaea01:29

Viruses of Archaea

212
Archaeal viruses play a crucial role in the ecosystems of extremophilic archaea, particularly those belonging to the phyla Euryarchaeota and Crenarchaeota. By shaping host evolution and facilitating gene transfer, these viruses influence microbial communities and contribute to genetic diversity in extreme environments. The archaea they infect thrive in acidic hot springs and hydrothermal vents characterized by high temperatures and low pH. Archaeal viruses exhibit remarkable structural...
212
Retroviruses02:33

Retroviruses

13.2K
Retroviruses and retrotransposons both insert copies of their genetic elements into the genome of the host cell. Thus, the viral genes are passed on when the host genome is replicated or translated. A typical retroviral DNA sequence contains 3-4 genes that encode the different proteins required for its structural assembly and function as a molecular parasite. This DNA is transcribed into a single mRNA, which is very similar in structure to conventional mRNAs, i.e., it is capped at the 5’...
13.2K
What are Viruses?00:50

What are Viruses?

122.3K
Overview
122.3K
Introduction to Virus01:28

Introduction to Virus

556
Viruses are unique biological entities that blur the boundary between living and non-living systems. Although they lack cellular structure and metabolic processes, they can exhibit characteristics of life when infecting a host. Their defining feature is a nucleic acid core, composed of either DNA or RNA, encapsulated within a protein coat called a capsid. This simple structure allows them to invade host cells and use their machinery for replication efficiently.Viral Structure and...
556
Viral Mutations00:36

Viral Mutations

36.4K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
36.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Medkour et al. Adenovirus Infections in African Humans and Wild Non-Human Primates: Great Diversity and Cross-Species Transmission. <i>Viruses</i> 2020, <i>12</i>, 657.

Viruses·2026
Same author

APOBEC cellular enzymes as 'court jesters' in SARS-CoV-2 evolution.

Virus genes·2026
Same author

Further dissection of <i>Gardnerella vaginalis</i>: description of <i>Gardnerella lacydonensis</i> sp. nov. (formerly genomic species 2), <i>Gardnerella bretellae</i> sp. nov. (formerly genomic species 9), <i>Gardnerella massiliensis</i> sp. nov. (formerly genomic species 14) and <i>Gardnerella phocaeensis</i> sp. nov.

International journal of systematic and evolutionary microbiology·2026
Same author

"Fertile" Mutations in SARS-CoV-2 RNA More Frequently Occurred in Hairpin Loops That Determine Virus Evolution.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica·2025
Same author

Air quality and particulate assessment in wood-heated military tents during arctic field training: implications for health and environmental safety.

BMJ military health·2025
Same author

MALDI-TOF mass spectrometry coupled with machine learning: an accurate tool to detect toxigenic Clostridioides difficile strains.

Anaerobe·2025

Related Experiment Video

Updated: Nov 1, 2025

A Rapid Strategy for the Isolation of New Faustoviruses from Environmental Samples Using Vermamoeba vermiformis
09:27

A Rapid Strategy for the Isolation of New Faustoviruses from Environmental Samples Using Vermamoeba vermiformis

Published on: June 4, 2016

7.9K

Marseilleviruses: An Update in 2021.

Dehia Sahmi-Bounsiar1,2, Clara Rolland1,2, Sarah Aherfi1,2

  • 1IHU Méditerranée Infection, Marseille, France.

Frontiers in Microbiology
|June 21, 2021
PubMed
Summary

Marseilleviruses, a family of giant viruses, are globally distributed in various environments and have been detected in humans. Their potential clinical significance is currently under investigation.

Keywords:
MarseilleviridaePimascoviralesamoebagiant virushumanmarseillevirusmegavirales

More Related Videos

Single Cell Micro-aspiration as an Alternative Strategy to Fluorescence-activated Cell Sorting for Giant Virus Mixture Separation
09:50

Single Cell Micro-aspiration as an Alternative Strategy to Fluorescence-activated Cell Sorting for Giant Virus Mixture Separation

Published on: October 27, 2019

7.3K
Lentivirus Production
11:42

Lentivirus Production

Published on: October 2, 2009

66.6K

Related Experiment Videos

Last Updated: Nov 1, 2025

A Rapid Strategy for the Isolation of New Faustoviruses from Environmental Samples Using Vermamoeba vermiformis
09:27

A Rapid Strategy for the Isolation of New Faustoviruses from Environmental Samples Using Vermamoeba vermiformis

Published on: June 4, 2016

7.9K
Single Cell Micro-aspiration as an Alternative Strategy to Fluorescence-activated Cell Sorting for Giant Virus Mixture Separation
09:50

Single Cell Micro-aspiration as an Alternative Strategy to Fluorescence-activated Cell Sorting for Giant Virus Mixture Separation

Published on: October 27, 2019

7.3K
Lentivirus Production
11:42

Lentivirus Production

Published on: October 2, 2009

66.6K

Area of Science:

  • Virology
  • Microbiology

Background:

  • The Marseilleviridae family, identified in 2013, is the second described family of giant viruses.
  • Marseillevirus marseillevirus, the prototype, was first isolated in 2007 from Acanthamoeba polyphaga.

Purpose of the Study:

  • To summarize the characteristics and distribution of the Marseilleviridae family.
  • To explore the potential clinical significance of marseilleviruses.

Main Methods:

  • Isolation of viruses from diverse environmental and human samples.
  • Genomic analysis of marseillevirus isolates.
  • Comparative genomic studies to understand viral lineages and pangenome.

Main Results:

  • Marseilleviruses are found worldwide in water, soil, insects, mussels, and humans.
  • Isolated viruses possess ~250 nm icosahedral capsids and genomes of 348-404 kilobases encoding 386-545 proteins.
  • Genomic analysis revealed five distinct lineages and a pangenome of 3,082 gene clusters.

Conclusions:

  • Marseilleviruses exhibit widespread distribution and genetic diversity.
  • Detection in human samples and persistence in animal models suggest a need for further investigation into their clinical relevance.