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Effects of comprehensive care in patients with multiple myeloma with cardiac dysfunction

Jinglu Xu1, Ru Bai2

  • 1Department of Hematology, Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University Huzhou 313000, Zhejiang Province, China.

American Journal of Translational Research
|June 21, 2021
PubMed

Insights

Comprehensive care significantly improves cardiac and renal function, treatment adherence, and quality of life in multiple myeloma patients with heart issues. This approach enhances self-care abilities and overall well-being.

Area of Science:

  • Cardiology
  • Nephrology
  • Oncology
  • Nursing Science

Background:

  • Multiple myeloma patients often experience cardiac dysfunction, impacting renal function and quality of life.
  • Managing these complex comorbidities requires effective, integrated care strategies.

Purpose of the Study:

  • To evaluate the impact of comprehensive care on cardiac and renal function indices.
  • To assess improvements in treatment compliance, self-care ability, and quality of life.
  • To determine the clinical significance of comprehensive care in this patient population.

Main Methods:

  • A randomized controlled trial involving 53 patients with multiple myeloma and cardiac dysfunction.
  • The experimental group received comprehensive care alongside routine nursing.
  • The control group received only routine nursing care.

Main Results:

  • Comprehensive care significantly improved left ventricular ejection fraction, brain natriuretic peptide, N-terminal pro-brain natriuretic peptide, glomerular filtration rate, serum creatinine, and uric acid levels.
  • Treatment compliance was significantly higher in the comprehensive care group (92.86%) compared to the control group (68%).
  • Self-care ability and quality of life scores were significantly elevated in the experimental group post-intervention.

Conclusions:

  • Comprehensive care demonstrates significant efficacy in enhancing cardiac and renal functions in patients with multiple myeloma and cardiac dysfunction.
  • This nursing approach substantially improves treatment compliance, self-care capacity, and overall quality of life.
  • Comprehensive care offers considerable clinical value for managing this complex patient group.
Abstract

Keywords:
Multiple myelomaquality of liferenal functionself-care abilitytreatment compliance

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