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Published on: February 18, 2015
Invasive Candidiasis Associated with Adenovirus Pneumonia
Guwani Liyanage1, Madhusha Gonapaladeniya2, Thushari Dissanayake2
1Department of Pediatrics, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
Abstract:
Invasive Candida infections in immunocompetent children lead to high morbidity and mortality despite available treatment. Candida albicans and Candida parapsilosis are the most common pathogens; however, there are newly emerging pathogenic non-albicans species. Adenovirus accounts for at least 5-10% of respiratory infections in children, and specific serotypes are associated with severe pneumonia. To the best of our knowledge, invasive Candida infection complicating adenovirus-associated pneumonia in immunocompetent children has not been reported previously. Herein, we describe a preschool child with invasive candidiasis associated with adenovirus pneumonia.
Insights
Invasive candidiasis complicating adenovirus pneumonia is a rare but serious condition in children. This case highlights the importance of considering fungal co-infections in severe pediatric respiratory illnesses.
Area of Science:
- Pediatric Infectious Diseases
- Mycology
- Virology
Background:
- Invasive candidiasis in children, even those immunocompetent, presents significant morbidity and mortality.
- Commonly implicated Candida species include C. albicans and C. parapsilosis, with emerging non-albicans species posing new threats.
- Adenovirus is a frequent cause of pediatric respiratory infections, with certain serotypes linked to severe pneumonia.
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