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A Case of Autoimmune Hemolytic Anemia Following COVID-19 Messenger Ribonucleic Acid Vaccination

Sérgio Brito1, Nuno Ferreira1, Sofia Mateus1

  • 1Internal Medicine, Hospital CUF Tejo, Lisbon, PRT.

Cureus
|June 21, 2021
PubMed

Autoimmune hemolytic anemia (AIHA) is a condition characterized by the increased destruction of red blood cells (RBCs) mediated by anti-erythrocyte autoantibodies with or without complement activation. Its clinical presentation is heterogeneous, ranging from asymptomatic to severe forms with fatal outcomes, and it can be either idiopathic or secondary to a coexisting disorder. In this report, we present a case of a patient who suffered from acute and severe AIHA after receiving the second dose of the coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccine.

Keywords:
autoimmune hemolytic anemiacovid-19 mrna vaccineimmune-mediated hemolysissars-cov-2warm autoimmune hemolytic anemia

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