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A decrease in macular microvascular perfusion after retinal detachment repair with silicone oil.

Wei Fang1, Jing Zhai1, Jian-Bo Mao1

  • 1The Eye Hospital of Wenzhou Medical University, School of Opthalmology & Optometry, WMU, Zhejiang Eye Hospital, Hangzhou 310000, Zhejiang Province, China.

International Journal of Ophthalmology
|June 21, 2021
PubMed
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Silicone oil tamponade after retinal detachment surgery may reduce superficial macular perfusion and retinal thickness compared to air. This effect can persist throughout the tamponade period, impacting visual recovery.

Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Vascular Biology

Background:

  • Retinal detachment repair often requires intraocular tamponade.
  • Silicone oil (SO) and air are common tamponading agents.
  • The impact of SO on macular perfusion post-retinal repair is not fully understood.

Purpose of the Study:

  • To investigate if silicone oil (SO) tamponade decreases macular perfusion after retinal detachment repair.
  • To compare macular perfusion and retinal thickness between SO and air tamponade groups.

Main Methods:

  • Prospective observational case-control study.
  • Included patients with primary macular-off rhegmatogenous retinal detachment undergoing vitrectomy.
  • Compared optical coherence tomography angiography findings at 1 and 3 months post-surgery between SO and air tamponade groups.
Keywords:
macular perfusionoptical coherence tomography angiographyretinal detachmentsilicone oilvessel density

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Main Results:

  • Silicone oil group showed decreased superficial parafoveal vessel density (PFSVD) at 1 and 3 months post-surgery.
  • Parafoveal deep vessel density (PFDVD) and foveal avascular zone area remained unchanged between groups.
  • Retinal thickness in the SO group was significantly reduced compared to the air group at both time points.

Conclusions:

  • Silicone oil tamponade is associated with reduced superficial macular perfusion and retinal thickness after retinal detachment surgery.
  • These perfusion and thickness changes may persist throughout the tamponade duration.
  • Air tamponade did not show similar reductions in macular perfusion or retinal thickness.