Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bioreactor Design and Operational System

Bioreactor Design and Operational System

Bioreactors are engineered vessels designed to cultivate microorganisms under controlled conditions for industrial bioprocessing. They maintain sterility and allow precise regulation of pH, temperature, oxygen, and nutrient levels to optimize microbial growth and metabolite production. Bioreactors range from small laboratory units of 1 liter to industrial systems holding up to 500,000 liters, though only about 75% of their volume is actively used for fermentation. The remaining headspace...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Trends and Disparities in Acute Myocardial Infarction-Related Mortality With Co-Listed Nicotine Dependence in the United States, 1999-2020.

Clinical cardiology·2026

Same author

Hidden Behind Ascites: An Atypical Pediatric Presentation of T-Cell Acute Lymphoblastic Leukemia-A Case Report.

Clinical case reports·2026

Same author

Multivariable analysis of myokines as biomarkers of frailty in females.

Experimental gerontology·2026

Same author

Temperature stress-induced production of salicylic acid from endophytic <i>Aspergillus flavus</i> with its <i>in silico</i> and <i>in vitro</i> anti-inflammatory potential and promising effect in combination with ibuprofen.

Frontiers in microbiology·2026

Same author

Type-5 diabetes mellitus: a call for clinical recognition and research prioritization.

Annals of medicine and surgery (2012)·2026

Same author

Using experimental results of protein design to guide biomolecular energy-function development.

PLoS computational biology·2026

Same journal

A CURE for synthetic regulation of gene expression: rapid screening of guide RNA efficacy as a framework for enabling undergraduate research in plant synthetic biology.

Synthetic biology (Oxford, England)·2026

Same journal

Chemically synthesized high-fidelity oligos ≤ 600 nt as building blocks to accelerate complex gene construction in synthetic biology.

Synthetic biology (Oxford, England)·2026

Same journal

Off-target detection of CRISPR-Cas9 nuclease <i>in vitro</i> with CROFT-Seq.

Synthetic biology (Oxford, England)·2026

Same journal

Going beyond size: exploring the metabolic burden in <i>Pseudomonas putida</i> during heterologous protein production.

Synthetic biology (Oxford, England)·2026

Same journal

A protein-fragment complementation assay to quantify synthetic protein scaffold efficiency.

Synthetic biology (Oxford, England)·2026

Same journal

EASY-C: Extraction and Analysis of Small Yeast Chromosomes-A rapid and universal platform for recovering artificial mini-chromosomes from synthetic Sc2.0 yeast and large plasmids from <i>Saccharomyces cerevisiae</i> and nonconventional yeast species.

Synthetic biology (Oxford, England)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 9, 2026

Development of New Methods for Quantifying Fish Density Using Underwater Stereo-video Tools

Development of New Methods for Quantifying Fish Density Using Underwater Stereo-video Tools

Published on: November 20, 2017

Aquarium: open-source laboratory software for design, execution and data management.

Justin Vrana¹, Orlando de Lange², Yaoyu Yang²

¹Department of Bioengineering, University of Washington, Seattle, WA, USA.

Synthetic Biology (Oxford, England)

|June 21, 2021

Summary

This summary is machine-generated.

Human-in-the-loop automation offers a cost-effective solution for labs to improve research reproducibility and scalability. Aquarium, an open-source software, integrates experimental design, inventory, and data capture for streamlined laboratory workflows.

Keywords:

LIMS automation replicability software

More Related Videos

Using the FishSim Animation Toolchain to Investigate Fish Behavior: A Case Study on Mate-Choice Copying In Sailfin Mollies

Using the FishSim Animation Toolchain to Investigate Fish Behavior: A Case Study on Mate-Choice Copying In Sailfin Mollies

Published on: November 8, 2018

Assessment of Swim Endurance and Swim Behavior in Adult Zebrafish

Assessment of Swim Endurance and Swim Behavior in Adult Zebrafish

Published on: November 12, 2021

Related Experiment Videos

Last Updated: Jun 9, 2026

Development of New Methods for Quantifying Fish Density Using Underwater Stereo-video Tools

Development of New Methods for Quantifying Fish Density Using Underwater Stereo-video Tools

Published on: November 20, 2017

Using the FishSim Animation Toolchain to Investigate Fish Behavior: A Case Study on Mate-Choice Copying In Sailfin Mollies

Using the FishSim Animation Toolchain to Investigate Fish Behavior: A Case Study on Mate-Choice Copying In Sailfin Mollies

Published on: November 8, 2018

Assessment of Swim Endurance and Swim Behavior in Adult Zebrafish

Assessment of Swim Endurance and Swim Behavior in Adult Zebrafish

Published on: November 12, 2021

Area of Science:

Biomedical research
Bioindustrial research
Life science laboratory research

Background:

Automation enhances replicability and scalability in scientific research.
High costs of robotic automation limit its adoption in academic labs.
Repetitive tasks in labs are often amenable to standardization.

Purpose of the Study:

To introduce human-in-the-loop automation as a viable solution for academic labs.
To present Aquarium, an open-source software for laboratory automation.
To detail the integration of experimental design, inventory management, protocol execution, and data capture.

Main Methods:

Development of Aquarium, an open-source, web-based software application.
Integration of key laboratory workflow components within a single platform.
Providing guidance on installation and usage for researchers.

Main Results:

Aquarium successfully integrates experimental design, inventory management, protocol execution, and data capture.
The software provides a framework for implementing human-in-the-loop automation.
Demonstrated potential for improving working practices and collaboration.

Conclusions:

Human-in-the-loop automation, facilitated by Aquarium, addresses the cost barrier to lab automation.
Aquarium supports biofoundries, collaboration, and education in life sciences.
The software promotes efficient and scalable research in life science laboratories.