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Updated: Nov 1, 2025

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Colposcopic outcomes for symptomatic patients with a negative oncogenic human papillomavirus test
Georgina Mitchell1, Jason Phung1, Elizabeth Holliday2,3
1Maternity and Gynaecology, John Hunter Hospital, New Lambton Heights, New South Wales, Australia.
Abstract:
This study assesses outcomes of colposcopy referrals for post-coital, intermenstrual, or other abnormal bleeding with negative oncogenic human papillomavirus and negative to low-grade cytology. Of 112 cases with median age of 34.5 years, cervical biopsy occurred in 19%, treatment of ectropion in 19%, endometrial sampling in 8%, polypectomy in 4%, and contraceptive change in 2%. No cervical or endometrial neoplasia was detected. Patients with bleeding symptoms and reassuring co-test may instead attend a general gynaecology clinic.

