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Published on: November 10, 2023
Diagnosis, prevention, and treatment of coronavirus disease: a review
Manoj Kumar Sarangi1, Sasmita Padhi1, Shrivardhan Dheeman2
1Department of Pharmaceutics, School of Pharmaceutical Sciences & Technology, Sardar Bhagwan Singh University, Balawala, Dehradun, Uttarakhand, India.
Insights
This review covers the epidemiology, virology, and treatment of Coronavirus disease (COVID-19), emphasizing nanotechnology, herbal antivirals, and AI for prevention. It highlights the need for vaccines and immunity-boosting measures for human survival.
Area of Science:
- Virology
- Epidemiology
- Pathogenesis
Background:
- Coronavirus disease (COVID-19) emerged in late 2019, rapidly escalating into a global pandemic with millions of cases and deaths worldwide.
- The World Health Organization reported over 172 million cases and 3.7 million deaths by June 2021.
Purpose of the Study:
- To provide a comprehensive review of COVID-19, including its epidemiology, virology, pathogenesis, transmission, and clinical aspects.
- To explore various treatment modalities, including antiviral agents, supportive therapies, nanotechnology-based approaches, and the potential of herbal and marine drugs.
- To discuss advancements in research, prevention strategies utilizing artificial intelligence, and the status of vaccine development globally.
Main Methods:
- Literature review encompassing epidemiology, virology, pathogenesis, genomic variations, transmission, clinical manifestations, diagnosis, and treatment strategies.
- Exploration of emerging therapeutic avenues such as nanotechnology, herbal/marine antivirals, and AI-driven prevention.
- Assessment of vaccine development progress and public health recommendations for immunity building.
Main Results:
- The review synthesizes current knowledge on COVID-19's multifaceted aspects, from viral characteristics to global impact.
- It highlights diverse treatment options and innovative approaches like nanotechnology and AI for disease control.
- The importance of immunity enhancement through lifestyle and the environmental benefits observed during the pandemic are noted.
Conclusions:
- Continued research and development of effective drugs and vaccines are crucial for combating the COVID-19 pandemic.
- Strengthening individual immunity through healthy lifestyle choices is vital for human survival.
- The pandemic underscores the interconnectedness of public health, scientific innovation, and environmental well-being.
Introduction:
Coronavirus disease (COVID-19) was first reported in Wuhan, China, in late December 2019 and subsequently, declared a pandemic. As of 3 June 2021, 172,493,290 individuals have acquired COVID-19 and 3,708,334 patients have died worldwide, according to the World Health Organization.
Areas Covered:
This review explores epidemiology; virology; pathogenesis; genomic variations; mode of transmission; clinical occurrence; diagnosis; and treatment with antiviral agents, antibiotics, and supportive therapies. It covers a nanotechnology-based treatment approach and emphasizes the importance of herbal and marine antiviral drugs. The review attempts to explain current advances in research, prevention, and control of COVID-19 spread through artificial intelligence and vaccine development status under cosmopolitan consideration.
Expert Opinion:
While COVID-19 research is advancing at full capacity, the discovery of drugs or vaccines that can fight the pandemic is necessary. Human survival in such a critical situation will be possible only with the development of strong immunity by opting for exercise, yoga, and consumption of hygienic food and beverages. Therefore, education about COVID-19 lethality and its impact on livelihood is important. The pandemic has also shown positive effects on the environment, such as a significant reduction in environmental pollution and global warming and improvement in river water quality.
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