Diagnosis, prevention, and treatment of coronavirus disease: a review

Manoj Kumar Sarangi1, Sasmita Padhi1, Shrivardhan Dheeman2

  • 1Department of Pharmaceutics, School of Pharmaceutical Sciences & Technology, Sardar Bhagwan Singh University, Balawala, Dehradun, Uttarakhand, India.

Insights

This review covers the epidemiology, virology, and treatment of Coronavirus disease (COVID-19), emphasizing nanotechnology, herbal antivirals, and AI for prevention. It highlights the need for vaccines and immunity-boosting measures for human survival.

Area of Science:

  • Virology
  • Epidemiology
  • Pathogenesis

Background:

  • Coronavirus disease (COVID-19) emerged in late 2019, rapidly escalating into a global pandemic with millions of cases and deaths worldwide.
  • The World Health Organization reported over 172 million cases and 3.7 million deaths by June 2021.

Purpose of the Study:

  • To provide a comprehensive review of COVID-19, including its epidemiology, virology, pathogenesis, transmission, and clinical aspects.
  • To explore various treatment modalities, including antiviral agents, supportive therapies, nanotechnology-based approaches, and the potential of herbal and marine drugs.
  • To discuss advancements in research, prevention strategies utilizing artificial intelligence, and the status of vaccine development globally.

Main Methods:

  • Literature review encompassing epidemiology, virology, pathogenesis, genomic variations, transmission, clinical manifestations, diagnosis, and treatment strategies.
  • Exploration of emerging therapeutic avenues such as nanotechnology, herbal/marine antivirals, and AI-driven prevention.
  • Assessment of vaccine development progress and public health recommendations for immunity building.

Main Results:

  • The review synthesizes current knowledge on COVID-19's multifaceted aspects, from viral characteristics to global impact.
  • It highlights diverse treatment options and innovative approaches like nanotechnology and AI for disease control.
  • The importance of immunity enhancement through lifestyle and the environmental benefits observed during the pandemic are noted.

Conclusions:

  • Continued research and development of effective drugs and vaccines are crucial for combating the COVID-19 pandemic.
  • Strengthening individual immunity through healthy lifestyle choices is vital for human survival.
  • The pandemic underscores the interconnectedness of public health, scientific innovation, and environmental well-being.
Abstract

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