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Related Concept Videos

Therapeutic Drug Monitoring: Overview and Classification01:16

Therapeutic Drug Monitoring: Overview and Classification

62
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
62
Pulse rhythm01:30

Pulse rhythm

1.0K
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
1.0K
Therapeutic Drug Monitoring: Drug Analysis Methods01:26

Therapeutic Drug Monitoring: Drug Analysis Methods

36
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...
36
Holter Monitor: 24-Hour Monitoring01:23

Holter Monitor: 24-Hour Monitoring

634
Holter monitoring is a continuous electrocardiography (ECG) recording that tracks the heart's electrical activity over an extended period, generally 24 to 48 hours. This noninvasive diagnostic tool detects irregular heart rhythms that may not be captured during a standard ECG performed in a clinical setting.DeviceThe Holter monitor is a portable, small device connected to several electrodes on the patient's chest. These electrodes detect the heart's electrical signals and transmit them to the...
634
Therapeutic Drug Monitoring: Affecting Factors01:29

Therapeutic Drug Monitoring: Affecting Factors

44
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
44
Drug Therapy01:28

Drug Therapy

131
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
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Updated: Nov 1, 2025

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
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Technology for Measuring and Monitoring Treatment Compliance Remotely.

Richard H Christie1, Anzar Abbas1, Vidya Koesmahargyo1

  • 1AiCure, New York, NY, USA.

Journal of Parkinson'S Disease
|June 21, 2021
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Summary
This summary is machine-generated.

Medication non-adherence in clinical trials is a major issue, especially for Parkinson's patients. Technology tools can now monitor medication in real-time, improving adherence and data quality for neurological studies.

Keywords:
Digital phenotypingParkinson’s diseaseremote measurementtreatment adherence

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Area of Science:

  • Clinical research methodology
  • Neurology
  • Pharmaceutical science

Background:

  • Medication non-adherence presents a significant challenge in clinical trials, potentially compromising safety and efficacy data.
  • Patients with neurological disorders, such as Parkinson's disease, face unique adherence obstacles due to symptoms like forgetfulness.

Purpose of the Study:

  • To explore the impact of technology-driven solutions on medication adherence in clinical trials.
  • To assess the potential of real-time monitoring tools to enhance data quality in studies involving patients with neurological conditions.

Main Methods:

  • Review of current technology tools designed for medication adherence monitoring.
  • Analysis of the application of these tools in clinical trial settings, particularly for neurological disorders.
  • Evaluation of the near real-time monitoring and dosage confirmation capabilities of these technologies.

Main Results:

  • Technology tools offer a promising approach to overcome traditional adherence barriers.
  • Real-time monitoring and dosage confirmation can significantly improve patient compliance.
  • Enhanced adherence directly contributes to higher quality safety and efficacy data.

Conclusions:

  • Technological interventions are crucial for improving medication adherence in clinical trials.
  • These tools have the potential to significantly enhance the reliability of data collected from studies, especially in complex patient populations.
  • Sponsors and clinical sites should consider adopting these technologies to strengthen trial integrity.