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Severe failure to thrive and diarrhoea caused by laxative abuse
A C Fenton1, M P Wailoo, M S Tanner
1Department of Child Health, Leicester Royal Infirmary.
Archives of Disease in Childhood
|August 1, 1988
Summary
Chronic use of Epsom salts in infants can cause severe diarrhea and weight loss. This case highlights the potential dangers of unsupervised magnesium sulfate administration in young children.
Area of Science:
- Pediatrics
- Gastroenterology
- Toxicology
Background:
- Magnesium sulfate (Epsom salts) is commonly used for various therapeutic purposes.
- Infant physiology differs significantly from adults, impacting drug metabolism and response.
- The safety of chronic Epsom salt administration in infants is not well-established.
Observation:
- A 7-month-old female infant presented with persistent diarrhea and significant weight loss.
- The infant had a history of chronic administration of Epsom salts.
- No other causative factors for the symptoms were identified.
Findings:
- Chronic Epsom salt administration was directly linked to the infant's severe diarrhea and failure to thrive.
- Excessive magnesium absorption is suspected as the underlying mechanism.
- The case underscores the potential for iatrogenic complications from over-the-counter medication misuse.
Implications:
- Healthcare providers should exercise caution when recommending or managing Epsom salt use in pediatric populations.
- Parents and caregivers need education on the risks associated with unsupervised administration of magnesium sulfate to infants.
- Further research is warranted to establish safe dosing guidelines and monitor for adverse effects of Epsom salts in children.