Related Experiment Video
Updated: Nov 1, 2025

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
Published on: November 1, 2015
Scurvy mimicking as systemic lupus erythematosus
Narueporn Likhitweerawong1, Nonglak Boonchooduang1, Wipawee Morakote2
1Paediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Insights
Scurvy, a vitamin C deficiency, is more common in children with autism due to restricted diets. Early nutritional assessment is crucial for timely diagnosis and treatment.
Area of Science:
- Nutrition
- Pediatrics
- Developmental Disorders
Background:
- Scurvy results from chronic vitamin C deficiency.
- Children with neurodevelopmental disorders, like autism spectrum disorder, have higher scurvy prevalence due to restricted diets.
Observation:
- A case of a child with autism presented with joint pain and anemia.
- Initial diagnosis considered systemic lupus erythematosus, leading to extensive testing and delayed identification of vitamin C deficiency.
Findings:
- Treatment with ascorbic acid (vitamin C) resolved the child's symptoms.
- This case underscores the link between restricted intake in autistic children and scurvy.
Implications:
- Emphasizes the importance of developmental and nutritional history in pediatric cases.
- Highlights the need for vigilance regarding nutritional status in children with selective eating habits.
Abstract:
Scurvy is a disease caused by chronic vitamin C deficiency. The greater prevalence was found in the paediatric population with neurodevelopmental disorders such as autism spectrum disorders due to their restricted dietary intake. Our case reported a child with autism who presented with arthralgia and anaemia. Systemic lupus erythematosus was the first diagnostic impression, resulting in over investigation and delayed diagnosis of vitamin C deficiency. After the child was treated with ascorbic acid, the child's symptoms resolved. This case highlighted the importance of developmental and nutritional history taking in the paediatric population. Furthermore, parents and physicians should be concerned about nutritional status, especially in children with restrictive dietary intake.
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency...
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune...
Endocarditis II: Clinical Features of Infective Endocarditis

