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Updated: Nov 1, 2025

Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System
Published on: December 29, 2023
Reducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk
Mark Kaddumukasa1, Josephine Najjuma2, Scovia Nalugo Mbalinda3
1Department of Medicine, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Introduction:
Stroke burden is rapidly increasing globally. Modifiable risk factors offer an opportunity to intervene, and targeting hypertension is a key actionable target for stroke risk reduction in sub-Saharan Africa. This 3-site planned randomized controlled trial builds on promising preliminary data.
Methods:
A total of 246 Ugandan adults will be recruited randomized to experimental intervention vs. enhanced treatment control. Intervention participants will receive six weekly group-format stroke risk reduction self-management training sessions, and the controls will receive information on cardiovascular risk. The primary study outcome is systolic B.P. measured at baseline, 13-week, 24 weeks (6 months). Secondary outcomes include other biological and behavioral stroke risk factors.
Discussion:
The curriculum-guided self-management TargetEd MAnageMent Intervention (TEAM) program is anticipated to reduce the stroke burden in Uganda.
Trial Registration:
ClinicalTrials.gov identifier: NCT04685408, registered on 28 December 2020.
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