Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

RNA sensors and actuators for dynamic cellular regulation.

Trends in biotechnology·2026
Same author

Construction of Peptide Amphiphile-Coated Coacervates with Selective Permeability.

ACS biomaterials science & engineering·2026
Same author

Protein-Based Nanostructures: Column-free Biosynthesis of Bundlemer Peptides with Programmable, Orthogonally Reactive Handles for Nanomaterial Construction.

ACS applied materials & interfaces·2025
Same author

Metabolite-responsive scaffold RNAs for dynamic CRISPR transcriptional regulation.

Nucleic acids research·2025
Same author

Synthetic protein degradation circuits using programmable cleavage and ligation by Sortase A.

Nature communications·2025
Same author

Leveraging endogenous MMPs for drug delivery in the cancer environment.

Expert opinion on drug delivery·2025

Related Experiment Video

Updated: Nov 1, 2025

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.5K

Engineering bionanoparticles for improved biosensing and bioimaging.

Daniel Yur1, Rachel M Lieser1, Millicent O Sullivan1

  • 1Department of Chemical and Biomolecular Engineering, University of Delaware, 150 Academy Street, Newark, DE 19716 United States.

Current Opinion in Biotechnology
|June 22, 2021
PubMed
Summary
This summary is machine-generated.

Bionanoparticles, like extracellular vesicles and protein nanoparticles, offer advanced bioimaging and biosensing capabilities. These platforms enable highly sensitive detection of various analytes, crucial for disease diagnosis and treatment.

More Related Videos

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications
11:28

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications

Published on: April 28, 2015

10.5K
Author Spotlight: High-Quality Quantum Dot Nanobeads for Sensitive Fluorescent Lateral Flow Immunoassays
07:13

Author Spotlight: High-Quality Quantum Dot Nanobeads for Sensitive Fluorescent Lateral Flow Immunoassays

Published on: June 28, 2024

1.7K

Related Experiment Videos

Last Updated: Nov 1, 2025

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.5K
Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications
11:28

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications

Published on: April 28, 2015

10.5K
Author Spotlight: High-Quality Quantum Dot Nanobeads for Sensitive Fluorescent Lateral Flow Immunoassays
07:13

Author Spotlight: High-Quality Quantum Dot Nanobeads for Sensitive Fluorescent Lateral Flow Immunoassays

Published on: June 28, 2024

1.7K

Area of Science:

  • Biotechnology
  • Nanotechnology
  • Medical Diagnostics

Background:

  • The COVID-19 pandemic highlighted the need for advanced bioimaging and biosensing technologies.
  • Accurate detection of viruses, tumors, glucose, and microbes is vital for disease management.
  • Bionanoparticles offer unique advantages for developing sensitive diagnostic tools.

Purpose of the Study:

  • To highlight the potential of bionanoparticles for bioimaging and biosensing applications.
  • To showcase how bionanoparticles can enhance detection sensitivity and specificity.
  • To demonstrate signal amplification strategies using bionanoparticle platforms.

Main Methods:

  • Utilizing protein nanoparticles and extracellular vesicles as bionanoparticle platforms.
  • Functionalizing bionanoparticle surfaces with sensing and detection modules.
  • Leveraging high surface functionalization and loading capacity of bionanoparticles.

Main Results:

  • Bionanoparticles enable high-density surface functionalization for improved analyte interaction.
  • Scaffolding sensing modules onto bionanoparticles enhances analyte affinity and specificity.
  • Demonstrated signal amplification leading to highly sensitive detection of analytes.

Conclusions:

  • Bionanoparticles are promising platforms for developing next-generation bioimaging and biosensing devices.
  • Protein nanoparticles and extracellular vesicles show significant potential for sensitive disease detection.
  • These platforms facilitate enhanced signal amplification for improved diagnostic performance.