Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Neural Spelling: A Spell-Based BCI System for Language Neural Decoding.

IEEE transactions on bio-medical engineering·2026

Same author

How to Match Cognitive Model Predictions With EEG Data.

Topics in cognitive science·2026

Same author

Editorial: Virtual and robotic embodiment.

Frontiers in neuroergonomics·2026

Same author

A Hybrid Covert Attention-Augmented Motor Imagery Paradigm for Brain-Computer Interfaces.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2026

Same author

Distinct effects of empathy on self-other processing revealed by different behavioral and EEG indices.

Cognitive, affective & behavioral neuroscience·2026

Same author

Virtual body ownership affects the processing of sensorimotor contingencies and goal-oriented information extraction, but not semantics.

NeuroImage·2026

Same journal

Turbulent flow in a vortex separator with a directed pipe inlet.

Scientific reports·2026

Same journal

Systematic characteristic evaluation of clay-based cementitious material derived from calcium carbide residue and waste tile powder.

Scientific reports·2026

Same journal

Retraction Note: Improvement of a rapid diagnostic application of monoclonal antibodies against avian influenza H7 subtype virus using Europium nanoparticles.

Scientific reports·2026

Same journal

Applying large language models to spam detection in the Kazakh low-resource language setting.

Scientific reports·2026

Same journal

An open-source 3D printing system enabling in-situ freeze-thaw processing of hydrogels.

Scientific reports·2026

Same journal

An enhanced EfficientNet framework for automated waste classification using cosine annealing and label smoothing.

Scientific reports·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Nov 1, 2025

Modeling the Functional Network for Spatial Navigation in the Human Brain

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Human brain dynamics in active spatial navigation.

Tien-Thong Nguyen Do¹, Chin-Teng Lin², Klaus Gramann^2,3,4

¹University of Technology Sydney, Faculty of Engineering and Information Technology, Australian Artificial Intelligence Institute, 15 Broadway, Ultimo, NSW, 2007, Australia. NguyenTienThong.Do@uts.edu.au.

Scientific Reports

|June 23, 2021

Summary

This summary is machine-generated.

This study shows that theta oscillations in the human retrosplenial complex (RSC) are linked to heading changes during active spatial navigation. This suggests the RSC plays a role in computing head direction in real-world movement scenarios.

More Related Videos

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

Using MazeSuite and Functional Near Infrared Spectroscopy to Study Learning in Spatial Navigation

Using MazeSuite and Functional Near Infrared Spectroscopy to Study Learning in Spatial Navigation

Published on: October 8, 2011

Related Experiment Videos

Last Updated: Nov 1, 2025

Modeling the Functional Network for Spatial Navigation in the Human Brain

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

Using MazeSuite and Functional Near Infrared Spectroscopy to Study Learning in Spatial Navigation

Using MazeSuite and Functional Near Infrared Spectroscopy to Study Learning in Spatial Navigation

Published on: October 8, 2011

Area of Science:

Neuroscience
Cognitive Science
Human Navigation

Background:

Spatial navigation relies on integrating sensory information processed by various brain networks.
The retrosplenial complex (RSC) is implicated in navigation, but prior studies used stationary setups, limiting ecological validity.
Previous research lacked insights into RSC function during active, real-world movement due to missing vestibular and proprioceptive inputs.

Purpose of the Study:

To investigate human retrosplenial complex (RSC) theta oscillations during active spatial navigation.
To determine if RSC activity correlates with heading computations in a dynamic environment.
To explore the role of physical rotations in inducing RSC theta activity.

Main Methods:

Utilized an active spatial navigation task involving ambulation between multiple locations.
Monitored participants' brain activity, focusing on theta oscillations (4-8 Hz) in the RSC.
Manipulated landmark and starting location positions during movement.

Main Results:

Theta power in the human RSC was significantly pronounced during heading changes.
RSC theta activity was not elevated during translational movements.
Evidence suggests physical rotations, not just translation, induce RSC theta oscillations.

Conclusions:

Human RSC theta oscillations are specifically associated with heading changes during active navigation.
Findings provide evidence for head-direction computation in the RSC during real-world spatial navigation.
This study bridges the gap between stationary and active navigation research in understanding RSC function.