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Intermediate-term results of a prospective, multicenter study on remote programming sacral neuromodulation for

Yaoguang Zhang1,2, Lingfeng Meng1,2, Peng Zhang3

  • 1Urology Department, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences Beijing, China.

Translational Andrology and Urology
|June 23, 2021
PubMed
Summary

The BetterStim sacral neuromodulation (SNM) system effectively treated refractory overactive bladder (OAB) over three years. This novel remote programming system demonstrated significant symptom improvement and a favorable safety profile in patients with OAB.

Keywords:
Sacral neuromodulation (SNM)overactive bladder (OAB)remote programming

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Area of Science:

  • Urology
  • Neuromodulation
  • Medical Devices

Background:

  • Refractory overactive bladder (OAB) significantly impacts quality of life.
  • Current treatments for OAB may have limitations or side effects.

Purpose of the Study:

  • To evaluate the long-term efficacy and safety of the BetterStim sacral neuromodulation (SNM) system.
  • To assess the impact of remote programming capabilities on OAB management.

Main Methods:

  • A multi-center study involving 84 patients with OAB, with 70 undergoing implantation of the BetterStim system.
  • Follow-up included in-person visits and subsequent telephone assessments over 3 years.
  • Outcomes measured via voiding diaries, OAB symptom scores, quality of life questionnaires, and adverse event monitoring.

Main Results:

  • A 79% success rate in overall OAB symptom improvement at 36 months.
  • Significant reductions in daily voids and urgency episodes, with increased voided volume.
  • Urge urinary incontinence episodes decreased significantly, and no remote programming-related adverse events were reported.

Conclusions:

  • The BetterStim SNM system with remote programming is a safe and effective treatment option for refractory OAB.
  • Intermediate-term results support the use of this technology for improving OAB symptoms and patient quality of life.