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Dopamine-2 receptor blockade does not affect the ocular hypotensive action of timolol
1Department of Clinical Pharmacology, St Bartholomew's Hospital Medical College, London.
The British Journal of Ophthalmology
|August 1, 1988
Abstract:
We have shown that metoclopramide, a dopamine-2 antagonist, failed to antagonise the ocular hypotensive action of timolol. The practical implication of combining dopamine agonists with beta-adrenoceptor antagonists in the treatment of glaucoma is discussed.