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Updated: Nov 1, 2025

Assessing the Viability of a Synthetic Bacterial Consortium on the In Vitro Gut Host-microbe Interface
Published on: July 4, 2018
ANTAGONISTIC ACTIVITY OF REPRESENTATIVES OF ORAL BIOCENOSIS
Natalya V Kotelevska1, Olha N Boychenko1, Yuliia V Sidash1
1POLTAVA STATE MEDICAL UNIVERSITY, POLTAVA, UKRAINE.
Objective:
The aim: Calculate the antagonistic activity of representatives of the oral biotope.
Patients And Methods:
Materials and methods: The mathematical techniques used in biotechnology and dentistry. The calculations were carried out on the basis of the research data obtained by the investigators from Ukrainian Medical Stomatological Academy (UMSA) (Poltava).
Results:
Results: The paper shows that the oral biocenosis is a group of microorganisms that have similar characteristics within the group, but different outside. This may indicate to the relationships between the bacteria, existing within such groups. A graphical demonstration of the associates of the oral biotope with different DMF represents their growth phases depending on the intensity of dental caries. The different slope and phases of the logistic curve of their growth may indicate certain relationships arising between groups of microorganisms.
Conclusion:
Conclusions: The symbiotic relationships within the oral biocenosis can be manifested by the antagonism, as indicated by the index of antagonistic activity, which in most cases can be calculated. Antagonistic activity can be determined more precisely, for which special techniques have been developed. Antagonistic activity of associates of biocenosis can serve as an indicator of the "conditionally pathogenic - pathogenic" transformation. Data on antagonistic activity can be used in oral hygiene activities and treatment of dental caries to impact the oral microbiocenosis. Data on antagonistic activity may have a predictive value.
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