Rapid Biocidal Activity of N-Halamine-Functionalized Polydopamine and Polyethylene Imine Coatings

Microorganisms easily adhere to the surface of substrates and further form biofilms, which present problems in various fields. Therefore, the development of surfaces with antimicrobial adhesion or viability is a promising approach. In this study, we were committed to develop a rapid sterilizing coating. First, polyester fibers were immersed into a mixing solution of dopamine (PDA) and polyethyleneimine (PEI) for forming the co-deposition of PDA and PEI coatings. After this, the co-deposition of PDA and PEI coatings was immersed in a solution of household bleach for chlorination. We found that the nitrogens of PDA and PEI could be chlorinated repeatedly and that the oxidative chlorine content increased with the increasing PEI concentration upon co-deposition. Next, the efficacy of the co-deposition of chlorinated PDA and PEI coatings in eliminating Staphylococcus aureus and Escherichia coli was investigated. We found that the antibacterial ability of the coatings increased with increasing PEI content. In addition, the chlorinated co-deposition coatings had significantly improved antibacterial properties compared to the unchlorinated ones. The chlorinated co-deposition coatings inactivated >99.99% of S. aureus and >99.9% of E. coli after contact of less than 10 min. Therefore, chlorination of a PDA/PEI co-deposition surface is a feasible method for use in antibacterial coatings.