[Changes in the blood-air barrier of the lungs in hyperthermia]

The influence of hyperthermia on the ultrastructure of lung air-blood barrier (ABB) was studied in experiments on dogs. It was shown that in hyperthermia both mean arithmetic and mean harmonic thickness of ABB were increased. The lung capillary endothelial layer was the most thick ABB layer, in which severe micropinocytosis could be observed. Marked destructive changes were noted in lung alveolar epithelial ABB layer up to the appearance of cell content in alveolar space and denudation of the epithelial basal membrane.