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Updated: Nov 1, 2025
Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
[Bowel resections for Crohn's disease: developments over the last three decades]
Igors Iesalnieks1, Ayman Agha1, Frank Dederichs2
1Klinik für Allgemein-, Viszeral-, Endokrine und Minimal-invasive Chirurgie, Klinik München Bogenhausen, München, Germany.
Surgical approaches for Crohn's disease have evolved significantly over 30 years. Recent trends show decreased stoma rates and morbidity with increased laparoscopic surgery and biologic use.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Inflammatory Bowel Disease Research
Background:
- Observational study detailing surgical advancements in Crohn's disease.
- Focus on patients undergoing bowel resection over three decades at tertiary centers.
Purpose of the Study:
- To analyze trends and developments in Crohn's disease surgery over 30 years.
- To compare surgical practices and outcomes across different time periods.
Main Methods:
- Retrospective and prospective data collection from 1992 to 2020.
- Inclusion of consecutive patients undergoing intestinal resections for Crohn's disease.
- Exclusion of specific cases like malignancy or non-Crohn's resections.
Main Results:
- Between 2000-2015: decreased steroid use, increased immunomodulator/biologic use, abandonment of mechanical bowel prep, increased laparoscopy, stoma rate, and morbidity.
- Since 2016: reintroduction of mechanical bowel prep, increased laparoscopic surgery (67%), decreased steroid/immunomodulator use, increased biologic use, older patients, fewer smokers, decreased stoma and morbidity rates.
Conclusions:
- Significant trends observed in Crohn's disease surgery over the last three decades.
- Findings may not be generalizable to all patient populations.
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