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COVID-19 and its Cardiac and Neurological Complications among Ontario Visible Minorities
Joseph Y Chu1, Yosuf Kaliwal2, Maria Koh2
1Division of Neurology, Department of Medicine, Toronto Western Hospital-University Health Network and William Osler Health System, University of Toronto, Toronto, Canada.
Insights
COVID-19 outcomes differed significantly between Chinese and South Asian populations in Ontario. Chinese individuals experienced higher mortality and neurological complications, while South Asians had lower mortality rates.
Area of Science:
- Epidemiology
- Public Health
- Infectious Diseases
Background:
- Limited data existed on COVID-19 complications in Ontario's Chinese and South Asian communities.
- Visible minorities faced a disproportionate impact from the pandemic.
Purpose of the Study:
- To systematically investigate the epidemiology of COVID-19.
- To analyze cardiac and neurological complications in Ontario's Chinese and South Asian populations.
- To compare outcomes with the general population.
Main Methods:
- Population-based retrospective study (Jan 1 - Sep 30, 2020).
- Identified COVID-19 positive Chinese and South Asians using a last name algorithm.
- Analyzed demographics, cardiac, and neurological complications, hospitalizations, and emergency visits.
Main Results:
- Chinese (older) had higher 30-day mortality (8.1%) vs. general population (5.0%).
- Chinese showed higher rates of neurological complications (160/10,000) compared to the general population (48/10,000).
- South Asians (younger) had lower 30-day mortality (2.1%) and fewer cardiac complications (64/10,000) than the general population (112/10,000).
Conclusions:
- Significant demographic and outcome differences observed in Chinese and South Asians with COVID-19.
- COVID-19 presented distinct challenges for these minority groups in Ontario.
- Further research is needed to understand these disparities.
Background:
Due to lack of data on the epidemiology, cardiac, and neurological complications among Ontario visible minorities (Chinese and South Asians) affected by coronavirus disease (COVID-19), this population-based retrospective study was undertaken to study them systematically.
Methods:
From January 1, 2020 to September 30, 2020 using the last name algorithm to identify Ontario Chinese and South Asians who were tested positive by PCR for COVID-19, their demographics, cardiac, and neurological complications including hospitalization and emergency visit rates were analyzed compared to the general population.
Results:
Chinese (N = 1,186) with COVID-19 were found to be older (mean age 50.7 years) compared to the general population (N = 42,547) (mean age 47.6 years) (p < 0.001), while South Asians (N = 3,459) were younger (age of 42.1 years) (p < 0.001). The 30-day crude rate for cardiac complications among Chinese was 169/10,000 (p = 0.069), while for South Asians, it was 64/10,000 (p = 0.008) and, for the general population, it was 112/10,000. For neurological complications, the 30-day crude rate for Chinese was 160/10,000 (p < 0.001); South Asians was 40/10,000 (p = 0.526), and general population was 48/10,000. The 30-day all-cause mortality rate was significantly higher for Chinese at 8.1% vs 5.0% for the general population (p < 0.001), while it was lower in South Asians at 2.1% (p < 0.001).
Conclusions:
Chinese and South Asians in Ontario affected by COVID-19 during the first wave of the pandemic were found to have a significant difference in their demographics, cardiac, and neurological outcomes.
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